Using Protein Structural Information to Understand the Mechanism of an Essential Enzyme for Fighting Tuberculosis

Using Protein Structural Information to Understand the Mechanism of an Essential Enzyme for Fighting Tuberculosis:  Antibiotic resistance is a global problem that many scientists are racing to solve. Researchers using the APS gained important insights into understanding the structure and mechanism of a critical enzyme involved in protein synthesis in tuberculosis, work that will form the basis of structure-based drug design efforts aimed at exploiting the unique features of this enzyme in developing new pharmaceuticals.